What is “CONTAINMENT”
con-tain-ment
noun
- the action of keeping something harmful under control or within limits
The overview of the functions and operations carried out within industry is always based on 3 basic elements:
- Product
- Personnel (operator)
- Environment
The concept of “containment” derives from these simple considerations, which provide a environment, or physical structure and activities, that can isolate the product from the other two elements.
Operator & Environmental Containment – Is needed in all process area where the process involves handling Active Pharmaceutical Ingredient (API) that can be harmful in anyway to the personnel of that environment.
Or
Aseptic Processing Containment – Required in process areas where the ingredients being handled need to be protected against external contamination arising from
- The Environment
- Personnel
- Bacterial Growth caused by the above
OEL: Occupational Exposure Limit
OHC: Occupational Health Categorisation
OEB: Occupational Exposure Band
TH: Toxic Hazard
ADI: Allowable Daily Intake
ADE: Allowable Daily Exposure
DEL: Design Exposure Limit
STEL: Short Term Exposure Limits
For example…
1 x grain of sugar equates to:
- 100µg – 647 x smaller than a typical grain of sugar
- 1µg – 64,790 x smaller than a typical grain of sugar
- 1ng – 64,790,000 x smaller than a typical grain of sugar
- Note: 1 grain of sugar = 0.06479g (1 grain troy)
- 64,790 microgrammes
- 64 790 000 nanogrammes